Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50043198
TargetHexokinase-4(Human)
Florida State University

Curated by ChEMBL
LigandPNGBDBM50248442(2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl...)
Affinity DataKd:  440nMAssay Description:Binding affinity to recombinant wild-type human pancreatic glucokinase expressed in Escherichia coli K-12 at 11 uM by isothermal titration calorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Florida State University

Curated by ChEMBL
LigandPNGBDBM50165031(6-[3-Isopropoxy-5-(2-thiophen-3-yl-ethoxy)-benzoyl...)
Affinity DataKd:  170nMAssay Description:Binding affinity to recombinant wild-type human pancreatic glucokinase expressed in Escherichia coli K-12 at 100 uM by isothermal titration calorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Florida State University

Curated by ChEMBL
LigandPNGBDBM50346020((2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-t...)
Affinity DataKd:  500nMAssay Description:Binding affinity to recombinant wild-type human pancreatic glucokinase expressed in Escherichia coli K-12 by isothermal titration calorimetry in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)