Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50043688
TargetAldo-keto reductase family 1 member B1(Rat)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049730BDBM50049730(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat kidney NADPH-dependent aldose reductase assessed as DL-glyceraldehyde conversion to glycerol preincubated for 20 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444638BDBM50444638(CHEMBL3098361)
Affinity DataIC50: 220nMAssay Description:Inhibition of rat kidney NADPH-dependent aldose reductase assessed as DL-glyceraldehyde conversion to glycerol preincubated for 20 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444641BDBM50444641(CHEMBL3098447)
Affinity DataIC50: 670nMAssay Description:Inhibition of rat kidney NADPH-dependent aldose reductase assessed as DL-glyceraldehyde conversion to glycerol preincubated for 20 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444640BDBM50444640(CHEMBL3098450)
Affinity DataIC50: 690nMAssay Description:Inhibition of rat kidney NADPH-dependent aldose reductase assessed as DL-glyceraldehyde conversion to glycerol preincubated for 20 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444642BDBM50444642(CHEMBL3098459)
Affinity DataIC50: 750nMAssay Description:Inhibition of rat kidney NADPH-dependent aldose reductase assessed as DL-glyceraldehyde conversion to glycerol preincubated for 20 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444639BDBM50444639(CHEMBL3098360)
Affinity DataIC50: 860nMAssay Description:Inhibition of rat kidney NADPH-dependent aldose reductase assessed as DL-glyceraldehyde conversion to glycerol preincubated for 20 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed