Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50005877
TargetSodium-dependent dopamine transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50495103(CHEMBL3105243)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]WIN35428 from human DAT after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50495101(CHEMBL1945251)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]Nisoxetine from human SERT after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50495101(CHEMBL1945251)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]WIN35428 from human DAT after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50495103(CHEMBL3105243)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]Nisoxetine from human SERT after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM22166(RTI 55, (exo,exo)-isomer, Iodine (125) labeled | R...)
Affinity DataKi:  6.30nMAssay Description:Binding affinity to DAT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKi:  17nMAssay Description:Binding affinity to DAT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50495101(CHEMBL1945251)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]Imipramin from human NET after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM22166(RTI 55, (exo,exo)-isomer, Iodine (125) labeled | R...)
Affinity DataKi:  29nMAssay Description:Binding affinity to SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM22166(RTI 55, (exo,exo)-isomer, Iodine (125) labeled | R...)
Affinity DataKi:  33nMAssay Description:Binding affinity to NET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50495102(CHEMBL3105242)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]WIN35428 from human DAT after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50495102(CHEMBL3105242)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]Nisoxetine from human SERT after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50495103(CHEMBL3105243)
Affinity DataKi:  153nMAssay Description:Displacement of [3H]Imipramin from human NET after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKi:  500nMAssay Description:Binding affinity to SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50495102(CHEMBL3105242)
Affinity DataKi:  785nMAssay Description:Displacement of [3H]Imipramin from human NET after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Medical University of Vienna

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to NET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed