Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50044058
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50336116(Ambenonium dichloride | CHEMBL1669479)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005114(CHEMBL3093804)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005115(CHEMBL3093802)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005116(CHEMBL3093803)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005181(CHEMBL3093797)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005180(CHEMBL3093798)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM10624(CHEMBL140020 | CHEMBL464538 | 1,5-bis(4-allyldimet...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005182(CHEMBL3093796)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005119(CHEMBL3093801)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005184(CHEMBL3093795)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005171(CHEMBL3093800)
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005182(CHEMBL3093796)
Affinity DataIC50: 350nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005181(CHEMBL3093797)
Affinity DataIC50: 370nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005179(CHEMBL3093799)
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005114(CHEMBL3093804)
Affinity DataIC50: 680nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005180(CHEMBL3093798)
Affinity DataIC50: 700nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005185(CHEMBL3093794)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005116(CHEMBL3093803)
Affinity DataIC50: 900nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005185(CHEMBL3093794)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005119(CHEMBL3093801)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005171(CHEMBL3093800)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005179(CHEMBL3093799)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005115(CHEMBL3093802)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM120262(Edrophonium Chloride, 3 | EDROPHONIUM CHLORIDE | E...)
Affinity DataIC50: 5.17E+3nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50336116(Ambenonium dichloride | CHEMBL1669479)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005184(CHEMBL3093795)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM10624(CHEMBL140020 | CHEMBL464538 | 1,5-bis(4-allyldimet...)
Affinity DataIC50: 3.54E+5nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM120262(Edrophonium Chloride, 3 | EDROPHONIUM CHLORIDE | E...)
Affinity DataIC50: 1.37E+6nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50336116(Ambenonium dichloride | CHEMBL1669479)
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50336116(Ambenonium dichloride | CHEMBL1669479)
Affinity DataKi:  6nMAssay Description:Non competitive inhibition of human recombinant AChE using ATChCl as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005114(CHEMBL3093804)
Affinity DataKi:  10nMAssay Description:Non competitive inhibition of human recombinant AChE using ATChCl as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005114(CHEMBL3093804)
Affinity DataKi:  20nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM10624(CHEMBL140020 | CHEMBL464538 | 1,5-bis(4-allyldimet...)
Affinity DataKi:  50nMAssay Description:Non competitive inhibition of human recombinant AChE using ATChCl as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005115(CHEMBL3093802)
Affinity DataKi:  400nMAssay Description:Non competitive inhibition of human recombinant AChE using ATChCl as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50005115(CHEMBL3093802)
Affinity DataKi:  400nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM10624(CHEMBL140020 | CHEMBL464538 | 1,5-bis(4-allyldimet...)
Affinity DataKi:  800nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM120262(Edrophonium Chloride, 3 | EDROPHONIUM CHLORIDE | E...)
Affinity DataKi:  4.80E+3nMAssay Description:Competitive inhibition of human recombinant AChE using ATChCl as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed