Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50005876
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50495099(CHEMBL3105705)
Affinity DataEC50:  110nMAssay Description:Modulation of p-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversal of paclitaxel resistanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50495100(CHEMBL3105238)
Affinity DataEC50:  94nMAssay Description:Modulation of p-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversal of paclitaxel resistanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataEC50:  32nMAssay Description:Modulation of p-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversal of paclitaxel resistanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataEC50:  446nMAssay Description:Modulation of p-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversal of paclitaxel resistanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed