Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50005677
TargetDNA topoisomerase 2-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50261768(CHEMBL2436126)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human DNA topoisomerase-2alpha assessed as relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50493595(CHEMBL1782155)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human DNA topoisomerase-2alpha assessed as relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50493598(CHEMBL2436123)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human DNA topoisomerase-2alpha assessed as relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50493593(CHEMBL2436122)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human DNA topoisomerase-2alpha assessed as relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50493592(CHEMBL2436124)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human DNA topoisomerase-2alpha assessed as relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50493596(CHEMBL2436125)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human DNA topoisomerase-2alpha assessed as relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50493597(CHEMBL2436127)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human DNA topoisomerase-2alpha assessed as relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50493594(CHEMBL2436128)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of human DNA topoisomerase-2alpha assessed as relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibition of human DNA topoisomerase-2alpha assessed as relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)