Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50043419
TargetHistone deacetylase 3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 106nMAssay Description:Inhibition of full length FLAG-tagged recombinant HDAC3 (unknown origin) transfected in human HeLa cells assessed as deacetylation of [3H]-acetylated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of HDAC3/NcoR2 (unknown origin) using RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440912(CHEMBL2431862)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of full length C-terminal His6x-tagged recombinant human HDAC3 expressed in baculovirus using Arg-His-Lys-Lys (Ac) as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HDAC3/NcoR2 (unknown origin) using RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440907(CHEMBL2431901)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of full length C-terminal His6x-tagged recombinant human HDAC3 expressed in baculovirus using Arg-His-Lys-Lys (Ac) as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440908(CHEMBL2431912)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length C-terminal His6x-tagged recombinant human HDAC3 expressed in baculovirus using Arg-His-Lys-Lys (Ac) as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440909(CHEMBL2431907)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length C-terminal His6x-tagged recombinant human HDAC3 expressed in baculovirus using Arg-His-Lys-Lys (Ac) as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440910(CHEMBL2431906)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length C-terminal His6x-tagged recombinant human HDAC3 expressed in baculovirus using Arg-His-Lys-Lys (Ac) as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440911(CHEMBL2431902)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length C-terminal His6x-tagged recombinant human HDAC3 expressed in baculovirus using Arg-His-Lys-Lys (Ac) as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed