Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50043332
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Eastern Finland
Curated by ChEMBL
University of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant GST-tagged SIRT1 using KI177 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Eastern Finland
Curated by ChEMBL
University of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant GST-tagged SIRT1 using KI177 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Eastern Finland
Curated by ChEMBL
University of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 using KI179 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Eastern Finland
Curated by ChEMBL
University of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 using KI179 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Eastern Finland
Curated by ChEMBL
University of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of human recombinant His-tagged SIRT3 using KI179 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Eastern Finland
Curated by ChEMBL
University of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 5.98E+3nMAssay Description:Inhibition of human recombinant GST-tagged SIRT1 using KI177 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Eastern Finland
Curated by ChEMBL
University of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 8.35E+3nMAssay Description:Inhibition of human recombinant His-tagged SIRT3 using KI179 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Eastern Finland
Curated by ChEMBL
University of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 using KI179 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Eastern Finland
Curated by ChEMBL
University of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of human recombinant His-tagged SIRT3 using KI179 as substrate preincubated for 5 mins followed by enzyme addition measured after 1 hr by ...More data for this Ligand-Target Pair
