Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50001496
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015935(CHEMBL85418 | 3-(1-Carboxy-2-phenyl-ethylcarbamoyl...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015938(CHEMBL85935 | 3-Chloromethyl-7-methoxy-5,5,8-triox...)
Affinity DataIC50: 430nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015931(CHEMBL313480 | 3-Benzenesulfonylmethyl-7-methoxy-5...)
Affinity DataIC50: 440nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015937(CHEMBL82964 | 3-(6-Hydroxy-2-methyl-5-oxo-2,5-dihy...)
Affinity DataIC50: 630nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015932(CHEMBL85310 | 3-Benzenesulfinylmethyl-7-methoxy-5,...)
Affinity DataIC50: 910nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015930(CHEMBL310354 | 7-Methoxy-5,5,8-trioxo-3-phenylsulf...)
Affinity DataIC50: 940nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015926(CHEMBL86006 | 7-Methoxy-3-methoxymethyl-5,5,8-trio...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015934(CHEMBL84205 | 3-Acetoxymethyl-7-methoxy-5,5,8-trio...)
Affinity DataIC50: 1.33E+3nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015925(7-Methoxy-3-(1-methyl-1H-tetrazol-5-ylsulfanylmeth...)
Affinity DataIC50: 1.62E+3nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015936(CHEMBL86253 | 3-Ethoxythiocarbonylsulfanylmethyl-7...)
Affinity DataIC50: 1.82E+3nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015939(CHEMBL84713 | 7-Methoxy-3-(5-methyl-[1,3,4]thiadia...)
Affinity DataIC50: 2.23E+3nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015929(CHEMBL314928 | 7-Methoxy-3-(1-methyl-1H-imidazol-2...)
Affinity DataIC50: 2.33E+3nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015933(CHEMBL85546 | 7-Methoxy-5,5,8-trioxo-3-(1H-[1,2,4]...)
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015927(CHEMBL309897 | (S)-7-Methoxy-3-methyl-5,5,8-trioxo...)
Affinity DataIC50: 3.15E+3nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015928(CHEMBL309710 | 2-Methoxy-3,3-dioxo-2,2a,3,4-tetrah...)
Affinity DataIC50: 5.78E+4nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015931(CHEMBL313480 | 3-Benzenesulfonylmethyl-7-methoxy-5...)
Affinity DataKi:  220nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015926(CHEMBL86006 | 7-Methoxy-3-methoxymethyl-5,5,8-trio...)
Affinity DataKi:  1.60E+3nMAssay Description:In vitro inhibitory activity against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed