Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50001490
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50228778(4,4''-Dihydroxyoctafluoroazobenzene | CHEMBL79036)
Affinity DataIC50: 790nMpH: 6.6Assay Description:Inhibition of rat testosterone-5 alpha-reductase activity at pH 6.6 from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataIC50: 1.60E+3nMpH: 6.6Assay Description:Inhibition of rat testosterone-5 alpha-reductase activity at pH 6.6 from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015844(CHEMBL309703 | 2,3,5,6-Tetrafluoro-4-pentafluoroph...)
Affinity DataIC50: 2.00E+3nMpH: 6.6Assay Description:Inhibition of rat testosterone-5 alpha-reductase activity at pH 6.6 from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataIC50: 2.60E+3nMpH: 7.4Assay Description:Inhibition of Testosterone-5 alpha-reductase activity at pH 7.4 from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50228778(4,4''-Dihydroxyoctafluoroazobenzene | CHEMBL79036)
Affinity DataIC50: 5.00E+3nMpH: 7.4Assay Description:Inhibition of Testosterone-5 alpha-reductase activity at pH 7.4 from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Steroid 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015844(CHEMBL309703 | 2,3,5,6-Tetrafluoro-4-pentafluoroph...)
Affinity DataIC50: 1.40E+4nMpH: 7.4Assay Description:Inhibition of Testosterone-5 alpha-reductase activity at pH 7.4 from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015846(CHEMBL78395 | 1,2,3,4,6,7,8,9-Octafluoro-5,11-dihy...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Steroid 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015844(CHEMBL309703 | 2,3,5,6-Tetrafluoro-4-pentafluoroph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015844(CHEMBL309703 | 2,3,5,6-Tetrafluoro-4-pentafluoroph...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015846(CHEMBL78395 | 1,2,3,4,6,7,8,9-Octafluoro-5,11-dihy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015843(CHEMBL79955 | 2,3,4,5-Tetrafluoro-6-pentafluorophe...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015843(CHEMBL79955 | 2,3,4,5-Tetrafluoro-6-pentafluorophe...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50228778(4,4''-Dihydroxyoctafluoroazobenzene | CHEMBL79036)
Affinity DataKi:  4.00E+3nMpH: 7.4Assay Description:Binding constant of Testosterone-5 alpha-reductase activity at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rat)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015844(CHEMBL309703 | 2,3,5,6-Tetrafluoro-4-pentafluoroph...)
Affinity DataKi:  1.00E+4nMpH: 7.4Assay Description:Binding constant of Testosterone-5 alpha-reductase activity at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed