Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50043292
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50368628(ABT-569 | Abbott-70569 | Abbott-70569.1 | Gabitril...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50039246((S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piper...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50419338(CHEMBL1446457)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50438758(CHEMBL2415009)
Affinity DataIC50: 5.48E+3nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50020883(CHEMBL77575 | (R)-Piperidine-3-carboxylic acid | N...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium- and chloride-dependent GABA transporter 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50039246((S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piper...)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of human GAT2 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50438758(CHEMBL2415009)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50438758(CHEMBL2415009)
Affinity DataIC50: 3.69E+4nMAssay Description:Inhibition of human GAT2 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50000102(omega-aminopropionic acid | Alanine-beta | beta-am...)
Affinity DataIC50: 4.12E+4nMAssay Description:Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50020883(CHEMBL77575 | (R)-Piperidine-3-carboxylic acid | N...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50039246((S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piper...)
Affinity DataIC50: 7.17E+4nMAssay Description:Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50438758(CHEMBL2415009)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50020888(CHEMBL77484 | (S)-nipecotic acid | (S)-Piperidine-...)
Affinity DataIC50: 1.16E+5nMAssay Description:Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50039246((S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piper...)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50000102(omega-aminopropionic acid | Alanine-beta | beta-am...)
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of human GAT2 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50020888(CHEMBL77484 | (S)-nipecotic acid | (S)-Piperidine-...)
Affinity DataIC50: 2.32E+6nMAssay Description:Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed