Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 6237
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
The Scripps Research Institute

LigandPNGBDBM24693(CHEMBL379094 | 2-({4-[6-(2,4-diamino-6-oxo-1,6-dih...)
Affinity DataKi:  30nMAssay Description:Enzyme activity assays of recombinant hGAR Tfase and recombinant hAICAR Tfase were performed as previously described. Kinetics of the enzyme reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
The Scripps Research Institute

LigandPNGBDBM24685(10R (8) | 2-({4-[(1R)-4-(2,4-diamino-6-oxo-1,6-dih...)
Affinity DataKi:  180nMAssay Description:Enzyme activity assays of recombinant hGAR Tfase and recombinant hAICAR Tfase were performed as previously described. Kinetics of the enzyme reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
The Scripps Research Institute

LigandPNGBDBM24686(10S (7) | 2-({4-[(1S)-4-(2,4-diamino-6-oxo-1,6-dih...)
Affinity DataKi:  210nMAssay Description:Enzyme activity assays of recombinant hGAR Tfase and recombinant hAICAR Tfase were performed as previously described. Kinetics of the enzyme reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
The Scripps Research Institute

LigandPNGBDBM24692(DDACTHF | 2-({4-[4-(2,4-diamino-6-oxo-1,6-dihydrop...)
Affinity DataKi:  1.70E+3nMAssay Description:Enzyme activity assays of recombinant hGAR Tfase and recombinant hAICAR Tfase were performed as previously described. Kinetics of the enzyme reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
The Scripps Research Institute

LigandPNGBDBM24692(DDACTHF | 2-({4-[4-(2,4-diamino-6-oxo-1,6-dihydrop...)
Affinity DataKi:  2.00E+4nMAssay Description:Enzyme activity assays of recombinant hGAR Tfase and recombinant hAICAR Tfase were performed as previously described. Kinetics of the enzyme reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
The Scripps Research Institute

LigandPNGBDBM24686(10S (7) | 2-({4-[(1S)-4-(2,4-diamino-6-oxo-1,6-dih...)
Affinity DataKi: >1.00E+5nMAssay Description:Enzyme activity assays of recombinant hGAR Tfase and recombinant hAICAR Tfase were performed as previously described. Kinetics of the enzyme reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
The Scripps Research Institute

LigandPNGBDBM24685(10R (8) | 2-({4-[(1R)-4-(2,4-diamino-6-oxo-1,6-dih...)
Affinity DataKi: >1.00E+5nMAssay Description:Enzyme activity assays of recombinant hGAR Tfase and recombinant hAICAR Tfase were performed as previously described. Kinetics of the enzyme reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
The Scripps Research Institute

LigandPNGBDBM24693(CHEMBL379094 | 2-({4-[6-(2,4-diamino-6-oxo-1,6-dih...)
Affinity DataKi: >1.00E+5nMAssay Description:Enzyme activity assays of recombinant hGAR Tfase and recombinant hAICAR Tfase were performed as previously described. Kinetics of the enzyme reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
The Scripps Research Institute

LigandPNGBDBM119131(Lometrexol (3))
Affinity DataKi: >1.00E+5nMAssay Description:Enzyme activity assays of recombinant hGAR Tfase and recombinant hAICAR Tfase were performed as previously described. Kinetics of the enzyme reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2014
Entry Details Article
PubMed