Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 6097
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University

LigandPNGBDBM50065935(NOB | CHEMBL98797 | Nitrosobenzene (Substrate 1) |...)
Affinity DataIC50: 2.08E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University

LigandPNGBDBM108226(1‐methyl‐2‐nitrosobenzene (Subst...)
Affinity DataIC50: 2.91E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University

LigandPNGBDBM108230(6‐hydroxy‐5‐nitrosonaphthalene&#...)
Affinity DataIC50: 3.54E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University

LigandPNGBDBM108229(6‐bromo‐1‐nitrosonaphthalen̴...)
Affinity DataIC50: 5.22E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University

LigandPNGBDBM108227(NDMA (Substrate 4))
Affinity DataIC50: 8.44E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University

LigandPNGBDBM108231(7‐methoxy‐1‐nitrosonaphthalen...)
Affinity DataIC50: 2.00E+6nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University

LigandPNGBDBM108232(1‐isopropyl‐3,5‐dimethyl‐4...)
Affinity DataIC50: 2.00E+6nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Escherichia coli (strain K12))
The Johns Hopkins University

LigandPNGBDBM108228(1‐nitroso‐2‐naphthol (Substrate ...)
Affinity DataKi:  4.22E+5nM ΔG°:  -20.0kJ/mole IC50: 1.07E+6nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures containing HEPES (100mM, pH 8.0, 2mM MgCl2, 5mM NaCl), ThDP (1mM), BSA (1mg/mL), DMSO (10%, v/v), ᴅ-GAP (30µM), pyruvate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed