Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50043176
TargetOxysterols receptor LXR-beta(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  103nMAssay Description:Agonist activity at human LXRbeta-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataEC50:  1.25E+5nMAssay Description:Agonist activity at human LXRbeta-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM20177((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3R)-3-hydroxy-6...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human LXRalpha-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  91nMAssay Description:Agonist activity at human LXRalpha-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human LXRalpha-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataKd:  103nMAssay Description:Binding affinity to human LXRbeta-LBD by surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataKd:  7.32E+4nMAssay Description:Binding affinity to human LXRbeta-LBD by surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataKd:  92nMAssay Description:Binding affinity to human LXRalpha-LBD by surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to human LXRalpha-LBD by surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed