Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50043171
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437010(CHEMBL2403024)
Affinity DataKd:  32nMAssay Description:Antagonist activity at NPY-Y2 receptor in human KAN-TS cell membranes assessed as inhibition of PYY-stimulated [35S]GTPgammaS binding preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437009(CHEMBL2403027)
Affinity DataKd:  4nMAssay Description:Antagonist activity at NPY-Y2 receptor in human KAN-TS cell membranes assessed as inhibition of PYY-stimulated [35S]GTPgammaS binding preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437008(CHEMBL2403028)
Affinity DataKd:  2nMAssay Description:Antagonist activity at NPY-Y2 receptor in human KAN-TS cell membranes assessed as inhibition of PYY-stimulated [35S]GTPgammaS binding preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437018(CHEMBL2403023)
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437018(CHEMBL2403023)
Affinity DataIC50: 7nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437017(CHEMBL2402905)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437008(CHEMBL2403028)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437017(CHEMBL2402905)
Affinity DataIC50: 13nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437009(CHEMBL2403027)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437014(CHEMBL2402906)
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437016(CHEMBL2402907)
Affinity DataIC50: 25nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437011(CHEMBL2403025)
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437007(CHEMBL2403029)
Affinity DataIC50: 33nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437010(CHEMBL2403024)
Affinity DataIC50: 37nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437007(CHEMBL2403029)
Affinity DataIC50: 45nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437016(CHEMBL2402907)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437015(CHEMBL2403026)
Affinity DataIC50: 162nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437014(CHEMBL2402906)
Affinity DataIC50: 210nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437013(CHEMBL2402909)
Affinity DataIC50: 476nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437012(CHEMBL2402908)
Affinity DataIC50: 665nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50352371(CHEMBL1823342)
Affinity DataIC50: 710nMAssay Description:Inhibition of MTP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437011(CHEMBL2403025)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437010(CHEMBL2403024)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437009(CHEMBL2403027)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50437008(CHEMBL2403028)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed