Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50005372
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491534(CHEMBL2380863)
Affinity DataIC50: 270nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491544(CHEMBL2380862)
Affinity DataIC50: 270nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 290nMAssay Description:Inhibition of COX-1 in human washed platelet assessed as inhibition of 0.5 uM arachidonic acid-induced TXB2 formation incubated for 25 mins prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491536(CHEMBL2380867)
Affinity DataIC50: 320nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491529(CHEMBL2380876)
Affinity DataIC50: 330nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 500nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491533(CHEMBL2380864)
Affinity DataIC50: 810nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491534(CHEMBL2380863)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491544(CHEMBL2380862)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of COX-1 in human washed platelet assessed as inhibition of 10 uM arachidonic acid-induced TXB2 formation incubated for 25 mins prior to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491543(CHEMBL2380865)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491526(CHEMBL2380866)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491545(CHEMBL2380874)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491529(CHEMBL2380876)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of arachidonic acid-induced TXB2 formation incubated for 5 mins p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491533(CHEMBL2380864)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of arachidonic acid-induced TXB2 formation incubated for 5 mins p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491542(CHEMBL2380870)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491536(CHEMBL2380867)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of arachidonic acid-induced TXB2 formation incubated for 5 mins p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491531(CHEMBL2380871)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491536(CHEMBL2380867)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of collagen-induced TXB2 formation incubated for 5 mins prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491529(CHEMBL2380876)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of collagen-induced TXB2 formation incubated for 5 mins prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491533(CHEMBL2380864)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of collagen-induced TXB2 formation incubated for 5 mins prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of arachidonic acid-induced TXB2 formation incubated for 5 mins p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491526(CHEMBL2380866)
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM93863(cid_827480 | MLS001179549 | SMR000475958 | 3,5-dip...)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491528(CHEMBL2380877)
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of collagen-induced TXB2 formation incubated for 5 mins prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491537(CHEMBL2380869)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491531(CHEMBL2380871)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of arachidonic acid-induced TXB2 formation incubated for 5 mins p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491545(CHEMBL2380874)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491531(CHEMBL2380871)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of COX-1 (unknown origin) in platelet rich plasma assessed as inhibition of collagen-induced TXB2 formation incubated for 5 mins prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491529(CHEMBL2380876)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491527(CHEMBL2380861)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491536(CHEMBL2380867)
Affinity DataIC50: 6.82E+4nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491532(CHEMBL2380868)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491527(CHEMBL2380861)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491528(CHEMBL2380877)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491530(CHEMBL2380873)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491540(CHEMBL2380872)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491531(CHEMBL2380871)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491539(CHEMBL2380879)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491532(CHEMBL2380868)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491533(CHEMBL2380864)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491535(CHEMBL2380880)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491530(CHEMBL2380873)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM93863(cid_827480 | MLS001179549 | SMR000475958 | 3,5-dip...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491535(CHEMBL2380880)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491541(CHEMBL2380878)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491543(CHEMBL2380865)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50491542(CHEMBL2380870)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
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