Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50005406
Target1,3-beta-D-glucan synthase catalytic subunit(Yeast)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of wild type Candida albicans MY1055 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Yeast)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50491848(CHEMBL2387201)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of wild type Candida albicans MY1055 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Yeast)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50491849(CHEMBL2387202)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of wild type Candida albicans 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Yeast)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50491851(CHEMBL2387203)
Affinity DataIC50: 18nMAssay Description:Inhibition of wild type Candida albicans 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Yeast)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50491850(CHEMBL2387205)
Affinity DataIC50: 35nMAssay Description:Inhibition of wild type Candida albicans 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Yeast)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50491847(CHEMBL3037784)
Affinity DataIC50: 36nMAssay Description:Inhibition of wild type Candida albicans 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed