Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50043060
TargetVasoactive intestinal polypeptide receptor 1(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50250019(PACAP | PACAP-38 | CHEMBL524658 | PACAP(1-38) | PA...)
Affinity DataIC50: 0.0500nMAssay Description:Binding affinity to human VPAC1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50015490(NPY, human, rat | CHEMBL438945 | NPY | H-YPSKPDNPG...)
Affinity DataIC50: 0.0700nMAssay Description:Binding affinity to human neuropeptide Y1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50015490(NPY, human, rat | CHEMBL438945 | NPY | H-YPSKPDNPG...)
Affinity DataIC50: 0.0900nMAssay Description:Binding affinity to human neuropeptide Y2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50435130(CHEMBL1893324)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity to human VPAC1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGalanin receptor type 1(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50378616(GALANIN)
Affinity DataIC50: 0.160nMAssay Description:Binding affinity to human GAL1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataIC50: 0.240nMAssay Description:Binding affinity to NTS1 receptor (unknown origin) by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50335566(CHEMBL1651026 | Substance P [Sar9,Met(O2)11])
Affinity DataIC50: 0.240nMAssay Description:Binding affinity to human NK1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50333104(H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2 | NC(1-17)NH2 ...)
Affinity DataIC50: 0.290nMAssay Description:Binding affinity to ORL1 receptor (unknown origin) by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGalanin receptor type 2(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50378616(GALANIN)
Affinity DataIC50: 0.800nMAssay Description:Binding affinity to human GAL2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM22567(CHEMBL511 | PYRILAMINE | 3H]pyrilamine | N-[2-(dim...)
Affinity DataIC50: 0.820nMAssay Description:Binding affinity to human histamine H1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50366495(CHEMBL1255588 | (+)butaclamol)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to human dopamine D2S receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM18207(dexamethasone (tetramethyl-rhodamine conjugated ) ...)
Affinity DataIC50: 2.5nMAssay Description:Binding affinity to human glucocorticoid receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50435131(CHEMBL2390989)
Affinity DataIC50: 2.5nMAssay Description:Binding affinity to human NK2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM82561(TROPANYL 3,5-DICHLOROBENZOATE | CAS_40796-97-2 | T...)
Affinity DataIC50: 4.90nMAssay Description:Binding affinity to human 5-HT3 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50051295(3-Methyl-2-phenyl-quinoline-4-carboxylic acid ((S)...)
Affinity DataIC50: 8.80nMAssay Description:Binding affinity to human NK3 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50435301(NPC-567 | CHEMBL446325)
Affinity DataIC50: 10nMAssay Description:Binding affinity to human bradykinin B2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM23954(CHEMBL494 | ILOPROST | 5-[(2E,3aS,4R,5R,6aS)-5-hyd...)
Affinity DataIC50: 13nMAssay Description:Binding affinity to PGI2 receptor (unknown origin) by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50435302(CHEMBL2391147)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]1,3-di(2-tolyl)guanidine from sigma 1 receptor in human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50403559(Brumetadina | CIMETIDINE)
Affinity DataIC50: 270nMAssay Description:Binding affinity to human histamine H2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]DTG from sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed