Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50005346
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey
Curated by ChEMBL
The State University of New Jersey
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of Keap1-Nrf2 interaction in human U2OS cells assessed as Nrf2 nuclear translocation by beta-lactamase reporter assayMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey
Curated by ChEMBL
The State University of New Jersey
Curated by ChEMBL
Affinity DataEC50: >1.00E+8nMAssay Description:Inhibition of Keap1-Nrf2 interaction in human HepG2 cells expressing ARE-bla assessed as activation of antioxidant response element by beta-lactamase...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey
Curated by ChEMBL
The State University of New Jersey
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of Keap1-Nrf2 interaction in human HepG2 cells expressing ARE-bla assessed as activation of antioxidant response element by beta-lactamase...More data for this Ligand-Target Pair
Affinity DataKd: 7.00E+5nMAssay Description:Binding affinity to Keap1 kelch domain (unknown origin) by competitive SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to Keap1 kelch domain (unknown origin) by competitive SPR assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 1.00E+5nMAssay Description:Binding affinity to Keap1 kelch domain (unknown origin) by competitive SPR assayMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey
Curated by ChEMBL
The State University of New Jersey
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of Keap1-Nrf2 interaction in human U2OS cells assessed as Nrf2 nuclear translocation by beta-lactamase reporter assayMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey
Curated by ChEMBL
The State University of New Jersey
Curated by ChEMBL
Affinity DataEC50: 1.20E+4nMAssay Description:Inhibition of Keap1-Nrf2 interaction in human U2OS cells assessed as Nrf2 nuclear translocation by beta-lactamase reporter assayMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey
Curated by ChEMBL
The State University of New Jersey
Curated by ChEMBL
Affinity DataEC50: 1.80E+4nMAssay Description:Inhibition of Keap1-Nrf2 interaction in human HepG2 cells expressing ARE-bla assessed as activation of antioxidant response element by beta-lactamase...More data for this Ligand-Target Pair
Affinity DataKd: 1.90E+3nMAssay Description:Binding affinity to Keap1 kelch domain (unknown origin) by competitive SPR assayMore data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey
Curated by ChEMBL
The State University of New Jersey
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Keap1-Nrf2 interaction (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
