Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50042943
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433560(CHEMBL2381409)
Affinity DataKd:  55nMAssay Description:Binding affinity to human MDM2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50111440(Ac-Phe-Met-Aib-Pmp-6-Cl-Trp-Glu-Ac3c-Leu-NH2, GST-...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50229787(CHEMBL191334 | 4-((4S,5R)-4,5-bis(4-chlorophenyl)-...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50392531(CHEMBL407632)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433562(Nutlin-1 | CHEMBL1818538)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433564(CHEMBL2381404)
Affinity DataIC50: 313nMAssay Description:Antagonist activity at human MDM2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433563(CHEMBL2381405)
Affinity DataIC50: 8.90E+3nMAssay Description:Antagonist activity at human MDM2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50433561(CHEMBL2381408)
Affinity DataKi:  10nMAssay Description:Binding affinity to human MDM2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed