Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50043053
TargetVasoactive intestinal polypeptide receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50435130(CHEMBL1893324)
Affinity DataIC50: 0.120nMAssay Description:Binding affinity to human VPAC1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50015490(NPY, human, rat | CHEMBL438945 | NPY | H-YPSKPDNPG...)
Affinity DataIC50: 0.140nMAssay Description:Binding affinity to human neuropeptide Y receptor type 1 by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50015490(NPY, human, rat | CHEMBL438945 | NPY | H-YPSKPDNPG...)
Affinity DataIC50: 0.190nMAssay Description:Binding affinity to human neuropeptide Y receptor type 2 by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50335566(CHEMBL1651026 | Substance P [Sar9,Met(O2)11])
Affinity DataIC50: 0.320nMAssay Description:Binding affinity to human NK1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataIC50: 0.330nMAssay Description:Binding affinity to human NTS1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGalanin receptor type 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50378616(GALANIN)
Affinity DataIC50: 0.770nMAssay Description:Binding affinity to human GAL1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM22567(CHEMBL511 | PYRILAMINE | 3H]pyrilamine | N-[2-(dim...)
Affinity DataIC50: 1.5nMAssay Description:Binding affinity to human histamine H1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50333104(H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2 | NC(1-17)NH2 ...)
Affinity DataIC50: 1.5nMAssay Description:Binding affinity to human NOP receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50366495(CHEMBL1255588 | (+)butaclamol)
Affinity DataIC50: 2.20nMAssay Description:Binding affinity to human dopamine D2S receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGalanin receptor type 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50378616(GALANIN)
Affinity DataIC50: 2.60nMAssay Description:Binding affinity to human GAL2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM18207(dexamethasone (tetramethyl-rhodamine conjugated ) ...)
Affinity DataIC50: 3nMAssay Description:Binding affinity to human glucocorticoid receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50435132(CHEMBL2392349)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant dopamine D2S receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM82561(TROPANYL 3,5-DICHLOROBENZOATE | CAS_40796-97-2 | T...)
Affinity DataIC50: 6.70nMAssay Description:Binding affinity to human 5-HT3 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50051295(3-Methyl-2-phenyl-quinoline-4-carboxylic acid ((S)...)
Affinity DataIC50: 7.10nMAssay Description:Binding affinity to human NK3 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM23954(CHEMBL494 | ILOPROST | 5-[(2E,3aS,4R,5R,6aS)-5-hyd...)
Affinity DataIC50: 8.40nMAssay Description:Binding affinity to human PGI2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50435131(CHEMBL2390989)
Affinity DataIC50: 9.20nMAssay Description:Binding affinity to human NK2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50435129(CHEMBL2392354)
Affinity DataIC50: 15nMAssay Description:Binding affinity to human bradykinin B2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50435133(CHEMBL2392351)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant dopamine D2S receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50403559(Brumetadina | CIMETIDINE)
Affinity DataIC50: 140nMAssay Description:Binding affinity to human histamine H2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetVasoactive intestinal polypeptide receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50435130(CHEMBL1893324)
Affinity DataKi:  0.0670nMAssay Description:Binding affinity to human VPAC1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50015490(NPY, human, rat | CHEMBL438945 | NPY | H-YPSKPDNPG...)
Affinity DataKi:  0.0760nMAssay Description:Binding affinity to human neuropeptide Y receptor type 2 by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50015490(NPY, human, rat | CHEMBL438945 | NPY | H-YPSKPDNPG...)
Affinity DataKi:  0.0960nMAssay Description:Binding affinity to human neuropeptide Y receptor type 1 by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50335566(CHEMBL1651026 | Substance P [Sar9,Met(O2)11])
Affinity DataKi:  0.140nMAssay Description:Binding affinity to human NK1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50130880(pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-L...)
Affinity DataKi:  0.270nMAssay Description:Binding affinity to human NTS1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGalanin receptor type 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50378616(GALANIN)
Affinity DataKi:  0.460nMAssay Description:Binding affinity to human GAL1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50333104(H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2 | NC(1-17)NH2 ...)
Affinity DataKi:  0.480nMAssay Description:Binding affinity to human NOP receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50366495(CHEMBL1255588 | (+)butaclamol)
Affinity DataKi:  0.740nMAssay Description:Binding affinity to human dopamine D2S receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM22567(CHEMBL511 | PYRILAMINE | 3H]pyrilamine | N-[2-(dim...)
Affinity DataKi:  0.950nMAssay Description:Binding affinity to human histamine H1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM18207(dexamethasone (tetramethyl-rhodamine conjugated ) ...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human glucocorticoid receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGalanin receptor type 2(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50378616(GALANIN)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to human GAL2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50051295(3-Methyl-2-phenyl-quinoline-4-carboxylic acid ((S)...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to human NK3 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM82561(TROPANYL 3,5-DICHLOROBENZOATE | CAS_40796-97-2 | T...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity to human 5-HT3 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM23954(CHEMBL494 | ILOPROST | 5-[(2E,3aS,4R,5R,6aS)-5-hyd...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to human PGI2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50435131(CHEMBL2390989)
Affinity DataKi:  5nMAssay Description:Binding affinity to human NK2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50435129(CHEMBL2392354)
Affinity DataKi:  7.90nMAssay Description:Binding affinity to human bradykinin B2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50403559(Brumetadina | CIMETIDINE)
Affinity DataKi:  140nMAssay Description:Binding affinity to human histamine H2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed