Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50042771
TargetVitamin D3 receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329704((R)-3-(4-(3-(4-((R)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at VDR (unknown origin) by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM36720(LG190155)
Affinity DataEC50:  40nMAssay Description:Agonist activity at VDR (unknown origin) by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430759(CHEMBL2334341)
Affinity DataEC50:  40nMAssay Description:Agonist activity at VDR (unknown origin) by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at CMX-GAL4 tagged human VDR expressed in HEK293 cells assessed as increase in transcriptional activity by luciferase reporter gene ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430750(CHEMBL2334345)
Affinity DataIC50: 72nMAssay Description:Antagonist activity at androgen receptor in androgen-dependent mouse SC3 cells assessed as inhibition of testosterone-induced cell growth after 3 day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430749(CHEMBL2334724)
Affinity DataIC50: 113nMAssay Description:Antagonist activity at androgen receptor in androgen-dependent mouse SC3 cells assessed as inhibition of testosterone-induced cell growth after 3 day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM35909(Eulexin | 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Mouse)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM35909(Eulexin | 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at androgen receptor in androgen-dependent mouse SC3 cells assessed as inhibition of testosterone-induced cell growth after 3 day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Mouse)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at androgen receptor in androgen-dependent mouse SC3 cells assessed as inhibition of testosterone-induced cell growth after 3 day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430749(CHEMBL2334724)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430757(CHEMBL2334342)
Affinity DataIC50: 5.80E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430758(CHEMBL1783642)
Affinity DataIC50: 6.20E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430755(CHEMBL2334344)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430750(CHEMBL2334345)
Affinity DataIC50: 6.80E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430750(CHEMBL2334345)
Affinity DataIC50: 7.40E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430756(CHEMBL2334343)
Affinity DataIC50: 8.30E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM36720(LG190155)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430751(CHEMBL2334349)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430752(CHEMBL2334348)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329704((R)-3-(4-(3-(4-((R)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM36721(LG190176)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430759(CHEMBL2334341)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430753(CHEMBL2334347)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50430754(CHEMBL2334346)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed