Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50042763
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human purified recombinant DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 127nMAssay Description:Inhibition of rat recombinant His-tagged truncated DHODH expressed in Escherichia coli using dihydroorotate as substrate by chromogen reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 367nMAssay Description:Inhibition of rat purified recombinant DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50203188(CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...)
Affinity DataIC50: 700nMAssay Description:Inhibition of rat purified recombinant DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50203188(CHEMBL1450 | 2-((1r,4r)-4-(4-chlorophenyl)cyclohex...)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of human purified recombinant DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed