Compile Data Set for Download or QSAR
Report error Found 170 Enz. Inhib. hit(s) with all data for entry = 50042717
LigandPNGBDBM50429896(CHEMBL2332918)
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429897(CHEMBL2333379)
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429895(CHEMBL2333375)
Affinity DataIC50: 137nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429893(CHEMBL2333373)
Affinity DataIC50: 238nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429892(CHEMBL2333374)
Affinity DataIC50: 259nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429891(CHEMBL2333366)
Affinity DataIC50: 398nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429890(CHEMBL2331575)
Affinity DataIC50: 459nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429889(CHEMBL2332922)
Affinity DataIC50: 670nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429888(CHEMBL2332929)
Affinity DataIC50: 693nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429887(CHEMBL2332928)
Affinity DataIC50: 705nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429886(CHEMBL2332920)
Affinity DataIC50: 763nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429885(CHEMBL2333378)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429884(CHEMBL2332921)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429883(CHEMBL2332919)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429882(CHEMBL2333372)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429881(CHEMBL2333370)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429880(CHEMBL2333376)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429879(CHEMBL2332923)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429878(CHEMBL2333371)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429877(CHEMBL2333362)
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429876(CHEMBL2333377)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429875(CHEMBL2333364)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429870(CHEMBL2333363)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429871(CHEMBL2332927)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429872(CHEMBL2332926)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429873(CHEMBL2332925)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429874(CHEMBL2332924)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429894(CHEMBL2333369)
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of p70S6K (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of KIT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of HSP90 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of FLT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of cRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CDC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
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