Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50042680
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in Wistar rat cortical membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-prazosin from alpha1B adrenergic receptor in Wistar rat liver membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50429260(CHEMBL2333732)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 dopamine receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 dopamine receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465](Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-RX821002 from alpha2A adrenergic receptor in Wistar rat cortical membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 dopamine receptor in Wistar rat brain striatal membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]-YM-09151-2 from human D4 dopamine receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]-OH-8-DPAT from 5HT1A receptor in Wistar rat hippocampal membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]-OH-8-DPAT from 5HT1A receptor in Wistar rat hippocampal membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  380nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 dopamine receptor in Wistar rat brain striatal membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50429260(CHEMBL2333732)
Affinity DataKi:  530nMAssay Description:Displacement of [3H]-YM-09151-2 from D2 dopamine receptor in Wistar rat brain striatal membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50429260(CHEMBL2333732)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]-prazosin from alpha1B adrenergic receptor in Wistar rat liver membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465](Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  2.49E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2A adrenergic receptor in Wistar rat cortical membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]-prazosin from alpha1B adrenergic receptor in Wistar rat liver membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50429260(CHEMBL2333732)
Affinity DataKi:  5.87E+3nMAssay Description:Displacement of [3H]-OH-8-DPAT from 5HT1A receptor in Wistar rat hippocampal membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465](Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50429260(CHEMBL2333732)
Affinity DataKi:  6.45E+3nMAssay Description:Displacement of [3H]-RX821002 from alpha2A adrenergic receptor in Wistar rat cortical membrane after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  6.82E+3nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in Wistar rat cortical membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50429260(CHEMBL2333732)
Affinity DataKi:  8.22E+3nMAssay Description:Displacement of [3H]-ketanserin from 5HT2A receptor in Wistar rat cortical membrane after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50308002(1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-p...)
Affinity DataKi:  8.44E+3nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Universidade Federal De Goi£S

Curated by ChEMBL
LigandPNGBDBM50429260(CHEMBL2333732)
Affinity DataKi:  1.23E+4nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed