Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50042420
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50425824(CHEMBL2312289)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to C-terminally His-tagged SIRT1 catalytic domain (241 to 516 amino acid residues plus EGHHHHHH) (unknown origin) expressed in bacul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50425824(CHEMBL2312289)
Affinity DataIC50: 98nMAssay Description:Inhibition of full length SIRT1 (unknown origin) by fluorometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed