Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50042413
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425717(CHEMBL2315934)
Affinity DataIC50: 5nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425696(CHEMBL2315931)
Affinity DataIC50: 5nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425695(CHEMBL2315932)
Affinity DataIC50: 7nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425716(CHEMBL2315935)
Affinity DataIC50: 7nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425697(CHEMBL2315930)
Affinity DataIC50: 7nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425714(CHEMBL2315937)
Affinity DataIC50: 8nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425705(CHEMBL2315922 | US9062048, 83)
Affinity DataIC50: 10nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425706(CHEMBL2315921 | US9062048, 78)
Affinity DataIC50: 15nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425707(CHEMBL2315920 | US9062048, 107)
Affinity DataIC50: 15nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425694(CHEMBL2315933)
Affinity DataIC50: 17nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425718(CHEMBL2316210)
Affinity DataIC50: 19nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425700(CHEMBL2315927)
Affinity DataIC50: 19nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425709(CHEMBL2316209)
Affinity DataIC50: 20nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425715(CHEMBL2315936)
Affinity DataIC50: 21nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425701(CHEMBL2315926)
Affinity DataIC50: 22nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425704(CHEMBL2315923)
Affinity DataIC50: 22nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425711(CHEMBL2315940 | US9062048, 61)
Affinity DataIC50: 23nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425702(CHEMBL2315925)
Affinity DataIC50: 27nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425698(CHEMBL2315929)
Affinity DataIC50: 36nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425708(CHEMBL2316211)
Affinity DataIC50: 38nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425713(CHEMBL2315938)
Affinity DataIC50: 39nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425703(CHEMBL2315924 | US9062048, 85)
Affinity DataIC50: 40nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425712(CHEMBL2315939 | US9062048, 82)
Affinity DataIC50: 50nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425699(CHEMBL2315928)
Affinity DataIC50: 56nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425710(CHEMBL2315941)
Affinity DataIC50: 72nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425715(CHEMBL2315936)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425707(CHEMBL2315920 | US9062048, 107)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425716(CHEMBL2315935)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425717(CHEMBL2315934)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425694(CHEMBL2315933)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425710(CHEMBL2315941)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425695(CHEMBL2315932)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425699(CHEMBL2315928)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425696(CHEMBL2315931)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425706(CHEMBL2315921 | US9062048, 78)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425697(CHEMBL2315930)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425714(CHEMBL2315937)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425704(CHEMBL2315923)
Affinity DataIC50: 2.84E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425700(CHEMBL2315927)
Affinity DataIC50: 2.85E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425713(CHEMBL2315938)
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425709(CHEMBL2316209)
Affinity DataIC50: 3.29E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425711(CHEMBL2315940 | US9062048, 61)
Affinity DataIC50: 3.51E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425712(CHEMBL2315939 | US9062048, 82)
Affinity DataIC50: 3.61E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425701(CHEMBL2315926)
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425698(CHEMBL2315929)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425705(CHEMBL2315922 | US9062048, 83)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425703(CHEMBL2315924 | US9062048, 85)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425702(CHEMBL2315925)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50425708(CHEMBL2316211)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed