Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50042649
TargetPeroxisome proliferator-activated receptor alpha(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50428826(CHEMBL2337127)
Affinity DataKd:  2.60E+3nMAssay Description:Binding affinity to human PPARalpha (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50173365(5-Chloro-1-(4-chloro-benzyl)-3-phenylsulfanyl-1H-i...)
Affinity DataKd:  29nMAssay Description:Binding affinity to human PPARgamma (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50099491(cid_3392731 | CHEMBL21241 | 2-(4-{2-[3-Cyclohexyl-...)
Affinity DataKd:  180nMAssay Description:Binding affinity to human PPARgamma (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM91427(4-methoxy-3-(3-methylbut-2-enyl)-2-oxidanyl-6-(2-p...)
Affinity DataEC50:  458nMAssay Description:Agonist at human PPARgamma LBD expressed in human HEK293 cells cotransfected with GAL4-Luc assessed as transcriptional activation by luciferase repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50428827(CHEMBL2337126)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist at human PPARgamma LBD expressed in human HEK293 cells cotransfected with GAL4-Luc assessed as transcriptional activation by luciferase repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50428826(CHEMBL2337127)
Affinity DataEC50:  50nMAssay Description:Agonist at human PPARgamma LBD expressed in human HEK293 cells cotransfected with GAL4-Luc assessed as transcriptional activation by luciferase repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataEC50:  4nMAssay Description:Agonist at human PPARgamma LBD expressed in human HEK293 cells cotransfected with GAL4-Luc assessed as transcriptional activation by luciferase repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM91427(4-methoxy-3-(3-methylbut-2-enyl)-2-oxidanyl-6-(2-p...)
Affinity DataKd:  2.70E+4nMAssay Description:Binding affinity to human PPARalpha (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50428827(CHEMBL2337126)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to human PPARalpha (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataKd:  7nMAssay Description:Binding affinity to human PPARgamma (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50099491(cid_3392731 | CHEMBL21241 | 2-(4-{2-[3-Cyclohexyl-...)
Affinity DataKd:  1nMAssay Description:Binding affinity to human PPARalpha (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM91427(4-methoxy-3-(3-methylbut-2-enyl)-2-oxidanyl-6-(2-p...)
Affinity DataKd:  2.70E+4nMAssay Description:Binding affinity to human PPARdelta (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50428827(CHEMBL2337126)
Affinity DataKd:  1.70E+4nMAssay Description:Binding affinity to human PPARdelta (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50428826(CHEMBL2337127)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to human PPARdelta (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50127222({4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl...)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to human PPARdelta (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM91427(4-methoxy-3-(3-methylbut-2-enyl)-2-oxidanyl-6-(2-p...)
Affinity DataKd:  236nMAssay Description:Binding affinity to human PPARgamma (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50428827(CHEMBL2337126)
Affinity DataKd:  287nMAssay Description:Binding affinity to human PPARgamma (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Helmholtz Centre For Infection Research

Curated by ChEMBL
LigandPNGBDBM50428826(CHEMBL2337127)
Affinity DataKd:  19nMAssay Description:Binding affinity to human PPARgamma (unknown origin) by competitive TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed