Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50042344
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424346(CHEMBL2314792)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of BACE1 in human SHSY5Y cells expressing APP NFEV and wild-type alpha-cleavage siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424345(CHEMBL2314793)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of BACE1 in human SHSY5Y cells expressing APP NFEV and wild-type alpha-cleavage siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424344(CHEMBL2314779)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of BACE1 in human SHSY5Y cells expressing APP NFEV and wild-type alpha-cleavage siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424346(CHEMBL2314792)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424345(CHEMBL2314793)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing modified BACE cleavage sequence of APP, NFEV and K612V mutationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424344(CHEMBL2314779)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing modified BACE cleavage sequence of APP, NFEV and K612V mutationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424345(CHEMBL2314793)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424346(CHEMBL2314792)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing modified BACE cleavage sequence of APP, NFEV and K612V mutationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424344(CHEMBL2314779)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424347(CHEMBL2314780)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424348(CHEMBL2314791)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424350(CHEMBL2314788)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424343(CHEMBL2314778)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of BACE1 in human SHSY5Y cells expressing APP NFEV and wild-type alpha-cleavage siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424349(CHEMBL2314789)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424343(CHEMBL2314778)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing modified BACE cleavage sequence of APP, NFEV and K612V mutationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424351(CHEMBL2314782)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50424352(CHEMBL2314781)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human recombinant BACE-1 using acetyl-C(W8044-Eu)-EVNLDAEFK-QSY7 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed