Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50042311
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423883(CHEMBL2312430)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423885(CHEMBL2312431)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423886(CHEMBL2312428)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423888(CHEMBL2312414)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423887(CHEMBL2312415)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50268295(2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDynamin-2(Rat)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423883(CHEMBL2312430)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of rat full length His6-tagged dyn2 using phosphatidylserine as substrate after 90 mins by malachite green GTPase assay in presence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDynamin-2(Human)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423884(CHEMBL2312432)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDynamin-2(Rat)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50268295(2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of rat full length His6-tagged dyn2 using phosphatidylserine as substrate after 90 mins by malachite green GTPase assay in presence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed