Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50040772
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399909(CHEMBL2180945)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399893(CHEMBL2180948)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399894(CHEMBL2180947)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399891(CHEMBL2180950)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399896(CHEMBL2180943)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399898(CHEMBL2180941)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399897(CHEMBL2180942)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399890(CHEMBL2180951)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399910(CHEMBL2180944)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399887(CHEMBL2180954)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399892(CHEMBL2180949)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399903(CHEMBL2180659)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399895(CHEMBL2180946)
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant PDE6C at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399889(CHEMBL2180952)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399909(CHEMBL2180945)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant PDE6C at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399888(CHEMBL2180953)
Affinity DataIC50: 58nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399904(CHEMBL2180658)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399905(CHEMBL2180657)
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399902(CHEMBL2180660)
Affinity DataIC50: 88nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399901(CHEMBL2180661)
Affinity DataIC50: 104nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399900(CHEMBL2180662)
Affinity DataIC50: 312nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399906(CHEMBL2180656)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399911(CHEMBL2180955)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399908(CHEMBL2180654)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399907(CHEMBL2180655)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399899(CHEMBL2180663)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399909(CHEMBL2180945)
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of human recombinant PDE11A4 at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 4.21E+3nMAssay Description:Inhibition of human recombinant PDE11A4 at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 4.69E+3nMAssay Description:Inhibition of human recombinant PDE7A1 at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE10A2 at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE9A2 at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE8A1 at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399909(CHEMBL2180945)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE10A2 at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399909(CHEMBL2180945)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE9A2 at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399909(CHEMBL2180945)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE8A1 at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399909(CHEMBL2180945)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE7A1 at 1 uM by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed