Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50040321
TargetNitric oxide synthase, inducible(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50392587(CHEMBL1230023)
Affinity DataIC50: 40nMAssay Description:Inhibition of wild type human iNOS expressed in Escherichia coli BL21(DE3) using L-Arg as substrate incubated for 1 hr prior to L-Arg additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50392587(CHEMBL1230023)
Affinity DataIC50: 200nMAssay Description:Inhibition of wild type human eNOS using L-Arg as substrate incubated for 1 hr prior to L-Arg additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50148162(Ethyl 4-[(4-methylpyridin-2-yl)amino]piperidine-1-...)
Affinity DataIC50: 350nMAssay Description:Inhibition of wild type human iNOS expressed in Escherichia coli BL21(DE3) using L-Arg as substrate incubated for 1 hr prior to L-Arg additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50148162(Ethyl 4-[(4-methylpyridin-2-yl)amino]piperidine-1-...)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of wild type human eNOS using L-Arg as substrate incubated for 1 hr prior to L-Arg additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)