Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50004814
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM50066789(A-85380,5-Iodo | CHEMBL123433 | A-85380-I | 3-((S)...)
Affinity DataKi:  0.0600nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat brain homogenate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM50486116(Niodene)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nAChR in Sprague-Dawley rat brain homogenate after 75 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM50486115(CHEMBL2207676)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM50066788(3-((S)-1-Azetidin-2-ylmethoxy)-2-fluoro-pyridine |...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat brain homogenate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]cytisine from alpha4beta2 nAChR in Sprague-Dawley rat brain homogenate after 75 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed