Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50040894
TargetSigma non-opioid intracellular receptor 1(Rat)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain membrane after 2.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Rat)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401675(CHEMBL2205361)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain membrane after 2.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401674(CHEMBL2205362)
Affinity DataKi:  27.5nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain membrane after 2.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401673(CHEMBL2205360)
Affinity DataKi:  34nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain membrane after 2.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401673(CHEMBL2205360)
Affinity DataKi:  204nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT2B receptor after 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401675(CHEMBL2205361)
Affinity DataKi:  249nMAssay Description:Displacement of [3H]clonidine from alpha2C adrenergic receptor after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401673(CHEMBL2205360)
Affinity DataKi:  653nMAssay Description:Displacement of [3H]clonidine from alpha2A adrenergic receptor after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401675(CHEMBL2205361)
Affinity DataKi:  936nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT2B receptor after 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401674(CHEMBL2205362)
Affinity DataKi:  945nMAssay Description:Displacement of [3H]clonidine from alpha2A adrenergic receptor after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401675(CHEMBL2205361)
Affinity DataKi:  1.23E+3nMAssay Description:Displacement of [3H]clonidine from alpha2A adrenergic receptor after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401674(CHEMBL2205362)
Affinity DataKi:  1.54E+3nMAssay Description:Displacement of [3H]clonidine from alpha2C adrenergic receptor after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401674(CHEMBL2205362)
Affinity DataKi:  2.56E+3nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor after 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401673(CHEMBL2205360)
Affinity DataKi:  2.77E+3nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor after 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401674(CHEMBL2205362)
Affinity DataKi:  2.87E+3nMAssay Description:Displacement of [3H]QNB from human recombinant M4 receptor after 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401675(CHEMBL2205361)
Affinity DataKi:  6.74E+3nMAssay Description:Displacement of [3H]N-methylspiperone from dopamine D3 receptor after 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401674(CHEMBL2205362)
Affinity DataKi:  7.61E+3nMAssay Description:Displacement of [3H]LY278584 from human recombinant 5-HT3 receptor after 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Savannah State University

Curated by ChEMBL
LigandPNGBDBM50401673(CHEMBL2205360)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]QNB from human recombinant M4 receptor after 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed