Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50040345
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392980(CHEMBL2152380)
Affinity DataIC50: 400nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced Gli1 transcriptional activity after 48 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)
Affinity DataIC50: 600nMAssay Description:Inhibition of human Shh-induced mouse C3H10T1/2 cell differentiation after 48 hrs by alkaline phosphatase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392980(CHEMBL2152380)
Affinity DataIC50: 600nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli1 transcriptional activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli-responsive betagalactosidase activity after 30 hrs by B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392980(CHEMBL2152380)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli-responsive betagalactosidase activity after 30 hrs by B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392980(CHEMBL2152380)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli1 transcriptional activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392964(CHEMBL2152364)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392976(CHEMBL2152376)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392970(CHEMBL2152370)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392981(CHEMBL2152381)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced Gli1 transcriptional activity after 48 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392957(CHEMBL2152357)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392979(CHEMBL2152379)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392975(CHEMBL2152375)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392973(CHEMBL2152373)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392962(CHEMBL2152362)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392971(CHEMBL2152371)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392972(CHEMBL2152372)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392961(CHEMBL2152361)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392959(CHEMBL2152359)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392976(CHEMBL2152376)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli-responsive betagalactosidase activity after 30 hrs by B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392976(CHEMBL2152376)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli1 transcriptional activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392977(CHEMBL2152377)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392955(CHEMBL2152355)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392965(CHEMBL2152365)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392954(CHEMBL2152354)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392956(CHEMBL2152356)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392960(CHEMBL2152360)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392978(CHEMBL2152378)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392963(CHEMBL2152363)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50311527((S,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-aza...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392958(CHEMBL2152358)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392969(CHEMBL2152369)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392966(CHEMBL2152366)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392974(CHEMBL2152374)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392967(CHEMBL2152367)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50249181(N-(4-chlorobenzyl)-2-((2R,6S,E)-5,12-dioxo-2-pheny...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human Shh-induced mouse C3H10T1/2 cell differentiation after 48 hrs by alkaline phosphatase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392968(CHEMBL2152368)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed