Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50004784
TargetPresenilin-1(Human)
Bristol-Myers Squibb R&D

Curated by ChEMBL
LigandPNGBDBM50485806(CHEMBL2164125)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human gamma-secretase expressed in IMR32 cell membranes using MBPC-125 Swedish as substrate assessed as inhibition of amyloid beta40 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb R&D

Curated by ChEMBL
LigandPNGBDBM50477715(CHEMBL248647)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP751 Swedish mutant assessed as inhibition of amyloid beta40 production after 19 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed