Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50040710
Target5-hydroxytryptamine receptor 4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataEC50: >1.00E+4nMAssay Description:Binding affinity to 5HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataEC50: >1.00E+4nMAssay Description:Binding affinity to 5HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataEC50: >1.00E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataEC50: >1.00E+4nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398714(CHEMBL2178742)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 5 mins by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 5 mins by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 5 mins by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398715(CHEMBL2178738)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 5 mins by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398715(CHEMBL2178738)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 10 mins by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 10 mins by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398714(CHEMBL2178742)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 10 mins by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 10 mins by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataKi:  303nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataKi:  536nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataKi:  586nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataKi:  682nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]astemizole from human ERG by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398712(CHEMBL2179216)
Affinity DataKi:  950nMAssay Description:Displacement of [3H]astemizole from human ERG by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataKi:  955nMAssay Description:Binding affinity to adrenergic alpha1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataKi:  1.81E+3nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataKi:  1.94E+3nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataKi:  1.96E+3nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataKi:  2.01E+3nMAssay Description:Binding affinity to NOR transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataKi:  2.13E+3nMAssay Description:Binding affinity to NOR transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataKi:  2.24E+3nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataKi:  2.37E+3nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataKi:  3.12E+3nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataKi:  3.22E+3nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataKi:  3.79E+3nMAssay Description:Binding affinity to adrenergic alpha1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398711(CHEMBL2179217)
Affinity DataKi:  6.37E+3nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398713(CHEMBL2179222)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398710(CHEMBL2178741)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]astemizole from human ERG by microbeta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed