Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50001352
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014955(CHEMBL350272 | 4-Hydroxy-6-[2-(2,4,7-trichloro-nap...)
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014949(CHEMBL424166 | 4-Hydroxy-6-[2-(2,4,6-trichloro-nap...)
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014956(CHEMBL444604 | 6-[2-(4,7-Dichloro-2-methyl-naphtha...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014954(CHEMBL350733 | 6-[2-(2,7-Dichloro-4-methyl-naphtha...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014948(CHEMBL164761 | 6-[2-(7-Chloro-2,4-dimethyl-naphtha...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014957(CHEMBL163734 | 4-Hydroxy-6-[2-(2,4,7-trimethyl-nap...)
Affinity DataIC50: 360nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014950(CHEMBL2368308 | 6-[2-(2-Chloro-naphthalen-1-yl)-vi...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014947(CHEMBL2368309 | 6-[2-(4-Bromo-naphthalen-1-yl)-vin...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014958(CHEMBL2368310 | 6-[2-(8-Bromo-naphthalen-1-yl)-vin...)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014953(CHEMBL164056 | 6-[2-(4,6-Dichloro-naphthalen-1-yl)...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014951(CHEMBL353120 | 6-[2-(4-Bromo-naphthalen-1-yl)-ethy...)
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014952(CHEMBL118866 | 4-Hydroxy-6-(2-naphthalen-1-yl-ethy...)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed