Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50042095
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50: 150nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 180nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50: 390nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50: 600nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50: 610nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420300(CHEMBL2089035)
Affinity DataIC50: 660nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 710nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420300(CHEMBL2089035)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420300(CHEMBL2089035)
Affinity DataIC50: 820nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420300(CHEMBL2089035)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse recombinant CLK1 expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of mouse recombinant CLK1 expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of mouse recombinant CLK1 expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed