Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50040261
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391645(CHEMBL2148050)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391642(CHEMBL2148051)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391649(CHEMBL2148044)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391645(CHEMBL2148050)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391641(CHEMBL2148048)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391647(CHEMBL2148045)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391642(CHEMBL2148051)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 11nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 11nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 11nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 11nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391646(CHEMBL2148046)
Affinity DataIC50: 11nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391648(CHEMBL2148047)
Affinity DataIC50: 14nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391649(CHEMBL2148044)
Affinity DataIC50: 15nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391644(CHEMBL2148049)
Affinity DataIC50: 17nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391641(CHEMBL2148048)
Affinity DataIC50: 18nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391647(CHEMBL2148045)
Affinity DataIC50: 31nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391644(CHEMBL2148049)
Affinity DataIC50: 47nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391646(CHEMBL2148046)
Affinity DataIC50: 53nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391648(CHEMBL2148047)
Affinity DataIC50: 56nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 160nMAssay Description:Inhibition of HER4 cytoplasmic domain after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal His6-tagged Aurora B expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 980nMAssay Description:Inhibition of N-terminal GST-tagged MEK1 after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of LCK after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of LYN B after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of LYN A after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of c-Met after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of CSK after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged GSK3beta expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-kit after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TIE2 after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of INSR after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged p38alpha expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged ASK1 expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length N-terminal FLAG-tagged FAK expressed in baculovirus after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged ERK1 expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged IKKbeta expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF-1R after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged TTK expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged MEKK expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Src after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR3 after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 after 5 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged VEGFR2 cytoplasmic domain expressed in baculovirus after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged PLK1 expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged MEK5 expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged JNK1 expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length N-terminal FLAG-tagged BMX expressed in baculovirus after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148053 | CHEMBL2148052)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ZAP70 after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
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