Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50042090
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50244787((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...)
Affinity DataIC50: 14nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform epsilon(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50399656(CHEMBL2069623 | US11633415, Compound PF4800567)
Affinity DataIC50: 32nMAssay Description:Inhibition of CK1epsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420281(CHEMBL2089212)
Affinity DataIC50: 78nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50364141(CHEMBL1951415)
Affinity DataIC50: 80nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform epsilon(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50364141(CHEMBL1951415)
Affinity DataIC50: 130nMAssay Description:Inhibition of CK1epsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420283(CHEMBL2089214)
Affinity DataIC50: 142nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50259376(3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino...)
Affinity DataIC50: 250nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50229971(4-[4-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-5-pyridin...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)
Affinity DataIC50: 450nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50399656(CHEMBL2069623 | US11633415, Compound PF4800567)
Affinity DataIC50: 711nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50263829(3-[(2,4,6-trimethoxyphenyl)methylidenyl]-indolin-2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420282(CHEMBL2089213)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM92674(Isoquinolinesulfonamide, CKI-7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420284(CHEMBL2089215)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50420285(CHEMBL2089216)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed