Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50040682
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398319(CHEMBL2177346)
Affinity DataEC50:  19.1nMAssay Description:Agonist activity at high sensitivity and low sensitivity alpha4beta2-nAChR expressed in human SH-EP1 cells by 86Rb+ ion flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398320(CHEMBL2177345)
Affinity DataEC50:  11.3nMAssay Description:Agonist activity at high sensitivity and low sensitivity alpha4beta2-nAChR expressed in human SH-EP1 cells by 86Rb+ ion flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398321(CHEMBL2177344)
Affinity DataEC50:  8.80nMAssay Description:Agonist activity at high sensitivity and low sensitivity alpha4beta2-nAChR expressed in human SH-EP1 cells by 86Rb+ ion flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398321(CHEMBL2177344)
Affinity DataIC50: 8.60nMAssay Description:Antagonist activity at high sensitivity and low sensitivity alpha4beta2-nAChR expressed in human SH-EP1 cells assessed as inhibition of carbamylcholi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398320(CHEMBL2177345)
Affinity DataIC50: 10.2nMAssay Description:Antagonist activity at high sensitivity and low sensitivity alpha4beta2-nAChR expressed in human SH-EP1 cells assessed as inhibition of carbamylcholi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50398319(CHEMBL2177346)
Affinity DataIC50: 22.2nMAssay Description:Antagonist activity at high sensitivity and low sensitivity alpha4beta2-nAChR expressed in human SH-EP1 cells assessed as inhibition of carbamylcholi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50382466(CHEMBL2024087)
Affinity DataKi:  12.8nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50382467(CHEMBL2024089)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholine-binding protein(Great pond snail)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  496nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSoluble acetylcholine receptor(California sea hare)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  598nMAssay Description:Displacement of [3H]epibatidine from Aplysia californica AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSoluble acetylcholine receptor(California sea hare)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50382466(CHEMBL2024087)
Affinity DataKi:  979nMAssay Description:Displacement of [3H]epibatidine from Aplysia californica AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSoluble acetylcholine receptor(California sea hare)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50382467(CHEMBL2024089)
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [3H]epibatidine from Aplysia californica AChBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed