Compile Data Set for Download or QSAR
Report error Found 119 Enz. Inhib. hit(s) with all data for entry = 50040661
LigandPNGBDBM50397973(CHEMBL2180441)
Affinity DataIC50: 0.00330nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397987(CHEMBL2180452)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50004081(CHEMBL2180797)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PDEDA2 using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397999(CHEMBL2180796)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PDEDA2 using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50398000(CHEMBL2180795)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PDEDA2 using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397988(CHEMBL2180806)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397972(CHEMBL2180442)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397977(CHEMBL2180420)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50390812(CHEMBL2069321)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of recombinant PDE10A1 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM31596(substituted pyrazole, 13)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant PDE10A by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM31592(PF-2545920 | substituted pyrazole, 9 | US9138494, ...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50398015(CHEMBL2180413 | US9018217, 5,7-dimethyl-2-(2-(1-me...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PDE10A using [3H]cAMP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50398017(CHEMBL2180411 | US9018217, 5,8-Dimethyl-2-[2-(1-me...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PDE10A using [3H]cAMP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397978(CHEMBL2180419)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397976(CHEMBL2180438)
Affinity DataIC50: 0.440nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397971(CHEMBL2180443)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397966(CHEMBL2180775)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant PDE10A1 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397974(CHEMBL2180440)
Affinity DataIC50: 0.890nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397989(CHEMBL2180805 | US8759532, 32)
Affinity DataIC50: 0.960nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM97527(US8470820, 38 | Roche-Dataset for PDE10A, Compound...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human full length PDE10A using [3H]cGMP as substrate after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM97529(US8470820, 40 | Roche-Dataset for PDE10A, Compound...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human full length PDE10A using [3H]cGMP as substrate after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397964(CHEMBL2180790)
Affinity DataIC50: 1nMAssay Description:Inhibition of PDEDA2 using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397979(US8927738, 5,8-Dimethyl-2-[2-(1-methyl-2-thiophen-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50390829(CHEMBL2070666)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant PDE10A1 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397993(CHEMBL2180406)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human full length PDE10A using [3H]cGMP as substrate after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397998(CHEMBL2180800 | US8470820, 62 | Roche-Dataset for ...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human full length PDE10A using [3H]cGMP as substrate after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397970(CHEMBL2180771)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant PDE2A expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397975(CHEMBL2180439)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50390822(CHEMBL2070659)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant PDE10A1 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397980(CHEMBL2180417)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397969(CHEMBL2180772)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of recombinant PDE2A expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397981(CHEMBL2180416)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397963(CHEMBL2180791)
Affinity DataIC50: 6nMAssay Description:Inhibition of PDEDA2 using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397994(CHEMBL2180405 | Roche-Dataset for PDE10A, Compound...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human full length PDE10A using [3H]cGMP as substrate after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397982(CHEMBL2180415)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50319165(2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant PDE10A1 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50319163(8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant PDE10A1 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50398001(CHEMBL2180794)
Affinity DataIC50: 7nMAssay Description:Inhibition of PDEDA2 using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50398014(CHEMBL2180414 | US9018217, 5,8-Dimethyl-2-[2-(1-me...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of PDE10A using [3H]cAMP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50398016(CHEMBL2180412 | US9018217, 5,8-Dimethyl-2-[2-(1-me...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of PDE10A using [3H]cAMP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397962(CHEMBL2180792)
Affinity DataIC50: 9nMAssay Description:Inhibition of PDEDA2 using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397968(CHEMBL2180773)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant PDE2A expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50397968(CHEMBL2180773)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of recombinant PDE10A1 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 30 mins by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50004074(CHEMBL2180002)
Affinity DataIC50: 10nMAssay Description:Inhibition of PDE10A using [3H]cAMP and [3H]cGMP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50004052(CHEMBL2180003)
Affinity DataIC50: 10nMAssay Description:Inhibition of PDE10A using [3H]cAMP and [3H]cGMP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50004075(CHEMBL2180001)
Affinity DataIC50: 10nMAssay Description:Inhibition of PDE10A using [3H]cAMP and [3H]cGMP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50004050(CHEMBL2180004)
Affinity DataIC50: 10nMAssay Description:Inhibition of PDE10A using [3H]cAMP and [3H]cGMP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50004054(CHEMBL2180005)
Affinity DataIC50: 10nMAssay Description:Inhibition of PDE10A using [3H]cAMP and [3H]cGMP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50003993(CHEMBL2180011)
Affinity DataIC50: 10nMAssay Description:Inhibition of human full length PDE10A expressed in SF21 cells using [3H]cGMP as substrate after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50003994(CHEMBL2180010 | US9579407, Example 00161)
Affinity DataIC50: 10nMAssay Description:Inhibition of human full length PDE10A expressed in SF21 cells using [3H]cGMP as substrate after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
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