Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50022515
TargetTyrosine-protein kinase JAK2(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase Chk1(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor alpha(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase Sgk1(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 3.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 8.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivated CDC42 kinase 1(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInsulin receptor(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivated CDC42 kinase 1(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50204589((S)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)f...)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 73nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 77nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50204589((S)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)f...)
Affinity DataIC50: 347nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 363nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50204589((S)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)f...)
Affinity DataIC50: 432nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 668nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50204589((S)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)f...)
Affinity DataIC50: 706nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50204589((S)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)f...)
Affinity DataIC50: 872nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 3.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 3.73E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed