Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50040052
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 70nMAssay Description:Inhibition of Cdc25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM41999(MLS-0111617.0001 | 3-(3,4,5-trihydroxy-6-oxo-9-xan...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM41999(MLS-0111617.0001 | 3-(3,4,5-trihydroxy-6-oxo-9-xan...)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM41999(MLS-0111617.0001 | 3-(3,4,5-trihydroxy-6-oxo-9-xan...)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate in presence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50388540(CHEMBL2059274)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM26617(4-[(2-carboxyphenyl)carbonyl]benzene-1,2-dicarboxy...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50388543(CHEMBL1481453)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50388539(CHEMBL1408031)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM26617(4-[(2-carboxyphenyl)carbonyl]benzene-1,2-dicarboxy...)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50388542(CHEMBL2059074)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50388537(CHEMBL1333982)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50388541(CHEMBL1370674)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50388538(CHEMBL507159)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50328823(5,5'-(3-(pyridin-2-yl)-1,2,4-triazine-5,6-diyl)dif...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50388538(CHEMBL507159)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50328823(5,5'-(3-(pyridin-2-yl)-1,2,4-triazine-5,6-diyl)dif...)
Affinity DataIC50: 1.73E+5nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM41999(MLS-0111617.0001 | 3-(3,4,5-trihydroxy-6-oxo-9-xan...)
Affinity DataKi:  70nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by Lineweav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM41999(MLS-0111617.0001 | 3-(3,4,5-trihydroxy-6-oxo-9-xan...)
Affinity DataKi:  80nMAssay Description:Competitive inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM26617(4-[(2-carboxyphenyl)carbonyl]benzene-1,2-dicarboxy...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by Lineweav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM26617(4-[(2-carboxyphenyl)carbonyl]benzene-1,2-dicarboxy...)
Affinity DataKi:  5.30E+3nMAssay Description:Competitive inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50388538(CHEMBL507159)
Affinity DataKi:  8.40E+4nMAssay Description:Competitive inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50328823(5,5'-(3-(pyridin-2-yl)-1,2,4-triazine-5,6-diyl)dif...)
Affinity DataKi:  1.39E+5nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by Lineweav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50328823(5,5'-(3-(pyridin-2-yl)-1,2,4-triazine-5,6-diyl)dif...)
Affinity DataKi:  1.59E+5nMAssay Description:Competitive inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50388538(CHEMBL507159)
Affinity DataKi:  2.03E+5nMAssay Description:Inhibition of recombinant phosphatase activity of Cdc25A catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by Lineweav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed