Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50039566
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50300811(N-{4-[4-(2,4-dimethoxyphenyl)-piperazin-1-yl]butyl...)
Affinity DataEC50:  2.84E+3nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50300802(CHEMBL1084615 | CHEMBL565540 | 5-Morpholin-4-ylpen...)
Affinity DataEC50:  9.50E+3nMAssay Description:Partial agonist activity at wild type rat recombinant alpha7 nAChR expressed in Xenopus oocyte by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50300802(CHEMBL1084615 | CHEMBL565540 | 5-Morpholin-4-ylpen...)
Affinity DataEC50:  1.65E+3nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380097(CHEMBL2012935)
Affinity DataKi:  3.90E+3nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380099(CHEMBL2012936)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380100(CHEMBL2012937)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380099(CHEMBL2012936)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380098(CHEMBL2010825)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380097(CHEMBL2012935)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50300802(CHEMBL1084615 | CHEMBL565540 | 5-Morpholin-4-ylpen...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380098(CHEMBL2010825)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380100(CHEMBL2012937)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380099(CHEMBL2012936)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380098(CHEMBL2010825)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380100(CHEMBL2012937)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50300802(CHEMBL1084615 | CHEMBL565540 | 5-Morpholin-4-ylpen...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50380097(CHEMBL2012935)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK292 cells after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed