Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50039562
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50179869(N-methyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50179869(N-methyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380068(CHEMBL2012766)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380070(CHEMBL2012768)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380067(CHEMBL2012765)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380069(CHEMBL2012767)
Affinity DataIC50: 500nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380070(CHEMBL2012768)
Affinity DataIC50: 700nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380064(CHEMBL2012762)
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380068(CHEMBL2012766)
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380064(CHEMBL2012762)
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380067(CHEMBL2012765)
Affinity DataIC50: 900nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380069(CHEMBL2012767)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380066(CHEMBL2012764)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380066(CHEMBL2012764)
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380065(CHEMBL2012763)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50380065(CHEMBL2012763)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed