Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50040034
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)
Affinity DataIC50: 0.300nMAssay Description:Competitive inhibition of BTK by TR-FRET based competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase Blk(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BLKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388185(CHEMBL2057919)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of BMXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388190(CHEMBL2057923)
Affinity DataIC50: 1nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50357333(CHEMBL1916891)
Affinity DataIC50: 1.93nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388181(CHEMBL2057913)
Affinity DataIC50: 2nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388180(CHEMBL2057912)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388185(CHEMBL2057919)
Affinity DataIC50: 11nMAssay Description:Inhibition of BTK in human Ramos cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388184(CHEMBL2057916)
Affinity DataIC50: 13nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388186(CHEMBL2057920)
Affinity DataIC50: 13nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388188(CHEMBL2057922)
Affinity DataIC50: 30nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 37nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388187(CHEMBL2057921)
Affinity DataIC50: 144nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50388182(CHEMBL2057914)
Affinity DataIC50: 400nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50357333(CHEMBL1916891)
Affinity DataIC50: 624nMAssay Description:Inhibition of LYNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM24941(CHEMBL228043 | alpha-cyano-beta-hydroxy-beta-methy...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant BTK expressed in baculovirus expression vector systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed