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Found
55
Enz. Inhib. hit(s) with all data for entry = 50039532
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50325177
(5-methyl-8-(1H-pyrrol-2-yl)-[1,2,4]triazolo[4,3-a]...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.100nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379546
(CHEMBL2012879)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379547
(CHEMBL2012859)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379548
(CHEMBL2012858)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379549
(CHEMBL2012857)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50243258
((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379550
(CHEMBL2012852)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379553
(CHEMBL2012878)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50325169
(8-(4-(hydroxymethyl)phenyl)-5-methyl-[1,2,4]triazo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379578
(CHEMBL2012856)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379552
(CHEMBL2012877)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379551
(CHEMBL2012863)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379557
(CHEMBL2012853)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50325175
(5-methyl-8-(thiophen-2-yl)-[1,2,4]triazolo[4,3-a]q...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379554
(CHEMBL2012841)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379561
(CHEMBL2012882)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379559
(CHEMBL2012880)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379558
(CHEMBL2012860)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379555
(CHEMBL2012842)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379556
(CHEMBL2012850)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379560
(CHEMBL2012881)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379566
(CHEMBL2012872)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379562
(CHEMBL2012848)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379563
(CHEMBL2012861)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379564
(CHEMBL2012865)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379565
(CHEMBL2012870)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379579
(CHEMBL2012883)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379570
(CHEMBL2012868)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379569
(CHEMBL2012862)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379567
(CHEMBL2012847)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379568
(CHEMBL2012855)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379571
(CHEMBL2012884)
Copy SMILES
Copy InChI
Affinity Data
IC50: 50nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379572
(CHEMBL2012871)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379577
(CHEMBL2012874)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379573
(CHEMBL2012866)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379574
(CHEMBL2012843)
Copy SMILES
Copy InChI
Affinity Data
IC50: 110nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379575
(CHEMBL2012864)
Copy SMILES
Copy InChI
Affinity Data
IC50: 130nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50243333
(1-(3-carbamoyl-5-(4-(2-(dimethylamino)ethoxy)pheny...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 150nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
PDB
3D Structure (crystal)
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379576
(CHEMBL2012839)
Copy SMILES
Copy InChI
Affinity Data
IC50: 160nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
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PubMed
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Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379581
(CHEMBL2012875)
Copy SMILES
Copy InChI
Affinity Data
IC50: 210nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379582
(CHEMBL2012873)
Copy SMILES
Copy InChI
Affinity Data
IC50: 240nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379583
(CHEMBL2012854)
Copy SMILES
Copy InChI
Affinity Data
IC50: 300nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379584
(CHEMBL2012867)
Copy SMILES
Copy InChI
Affinity Data
IC50: 300nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Vascular endothelial growth factor receptor 2
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379560
(CHEMBL2012881)
Copy SMILES
Copy InChI
Affinity Data
IC50: 319nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379585
(CHEMBL2012876)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379586
(CHEMBL2012840)
Copy SMILES
Copy InChI
Affinity Data
IC50: 420nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379545
(CHEMBL2012844)
Copy SMILES
Copy InChI
Affinity Data
IC50: 440nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379587
(CHEMBL2012845)
Copy SMILES
Copy InChI
Affinity Data
IC50: 440nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379588
(CHEMBL2012846)
Copy SMILES
Copy InChI
Affinity Data
IC50: 560nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Serine/threonine-protein kinase Chk1
(Human)
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379589
(CHEMBL2012851)
Copy SMILES
Copy InChI
Affinity Data
IC50: 600nM
Assay Description:
Inhibition of Chk1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/7/2013
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
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