Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50001278
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006689(CHEMBL169981 | 2-{2-Fluoro-4-[(2-methyl-4-oxo-3,4-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006687((S)-2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50: 40nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014501(CHEMBL104358 | 2-{2-Fluoro-4-[(2-fluoro-ethyl)-(2-...)
Affinity DataIC50: 43nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014506(CHEMBL104856 | (S)-2-(4-(ethyl((2-methyl-4-oxo-3,4...)
Affinity DataIC50: 45nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014518(CHEMBL323363 | (S)-2-(2-methoxy-4-(((2-methyl-4-ox...)
Affinity DataIC50: 67nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014514(CHEMBL323375 | (S)-2-(2-chloro-4-(((2-methyl-4-oxo...)
Affinity DataIC50: 74nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014516(2-{4-[Allyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin...)
Affinity DataIC50: 76nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014505(CHEMBL105425 | (S)-2-(2-fluoro-4-((2-hydroxyethyl)...)
Affinity DataIC50: 78nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014527(CHEMBL320621 | 2-{2-Hydroxy-4-[(2-methyl-4-oxo-3,4...)
Affinity DataIC50: 90nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006694(2-{2-Fluoro-4-[methyl-(2-methyl-4-oxo-3,4-dihydro-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014517(CHEMBL105899 | (S)-2-(2-chloro-4-(ethyl((2-methyl-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014509(CHEMBL320464 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-q...)
Affinity DataIC50: 130nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014500(CHEMBL101425 | (S)-2-(4-(ethyl((2-methyl-4-oxo-3,4...)
Affinity DataIC50: 145nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014504((S)-2-(4-((cyanomethyl)((2-methyl-4-oxo-3,4-dihydr...)
Affinity DataIC50: 170nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012045(2-{4-[Ethyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin...)
Affinity DataIC50: 170nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014520(2-{4-[Ethyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin...)
Affinity DataIC50: 190nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014473(CHEMBL104759 | 2-{4-[(2-Fluoro-ethyl)-(2-methyl-4-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014507((S)-2-(2-amino-4-(((2-methyl-4-oxo-3,4-dihydroquin...)
Affinity DataIC50: 290nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006691(CHEMBL40321 | (S)-2-(4-(methyl((2-methyl-4-oxo-3,4...)
Affinity DataIC50: 300nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014499((S)-2-(2-amino-4-(ethyl((2-methyl-4-oxo-3,4-dihydr...)
Affinity DataIC50: 310nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014524(CHEMBL104871 | 2-{4-[Ethyl-(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50: 320nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014481(CHEMBL323539 | 2-{4-[Allyl-(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50: 480nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014522(CHEMBL102938 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-q...)
Affinity DataIC50: 480nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014526(CHEMBL323294 | (S)-2-(2-methyl-4-(((2-methyl-4-oxo...)
Affinity DataIC50: 500nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014486(CHEMBL104025 | 2-{4-[(2-Hydroxy-ethyl)-(2-methyl-4...)
Affinity DataIC50: 500nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014469(CHEMBL104748 | 2-{4-[(3-Hydroxy-propyl)-(2-methyl-...)
Affinity DataIC50: 540nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014512((S)-2-(2-fluoro-4-((3-hydroxypropyl)((2-methyl-4-o...)
Affinity DataIC50: 590nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014503(CHEMBL105384 | 2-{4-[Ethyl-(2-methyl-4-oxo-3,4-dih...)
Affinity DataIC50: 680nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014502(CHEMBL105597 | 2-{2-Amino-4-[methyl-(2-methyl-4-ox...)
Affinity DataIC50: 860nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014521((S)-2-(2-methyl-4-(methyl((2-methyl-4-oxo-3,4-dihy...)
Affinity DataIC50: 940nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014510(CHEMBL104670 | 2-{3-Fluoro-4-[(3-hydroxy-propyl)-(...)
Affinity DataIC50: 980nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006690((S)-2-(3-fluoro-4-(methyl((2-methyl-4-oxo-3,4-dihy...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014525(2-{4-[Carbamoylmethyl-(2-methyl-4-oxo-3,4-dihydro-...)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50006684((S)-2-(3-fluoro-4-(((2-methyl-4-oxo-3,4-dihydroqui...)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014519(CHEMBL105150 | 2-{3-Fluoro-4-[(2-fluoro-ethyl)-(2-...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014508(CHEMBL104624 | (S)-2-(3-fluoro-4-((2-hydroxyethyl)...)
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014513(CHEMBL104533 | 2-{2-Fluoro-4-[(2-methyl-4-oxo-3,4-...)
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012516(CHEMBL70515 | 2-{4-[(2-Methyl-4-oxo-3,4-dihydro-qu...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014515(CHEMBL105208 | (S)-2-(4-(allyl((2-methyl-4-oxo-3,4...)
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014523(CHEMBL104267 | 2-{3-Fluoro-4-[(2-methyl-4-oxo-3,4-...)
Affinity DataIC50: 9.34E+3nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50014511(CHEMBL104110 | (S)-2-(4-((2-aminoethyl)((2-methyl-...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of partially purified thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed